Intracranial pressure (ICP)

Monitoring intracranial pressure - ICP - during preclinical studies in small animals is challenging. Samba Sensors' systems are being used both in trauma and post trauma studies to measure intracranial pressure.

In post trauma studies intracranial swelling is a slow process associated with small pressure changes. By measuring these changes with a Samba Sensors' system it is possible to follow this process directly in the brain tissues. As an example, see the publication http://www.ncbi.nlm.nih.gov/pubmed/18586012.

Similarly, in trauma research studies in animal models it is possible to induce trauma and, during the critical microseconds that follow, monitor how the pressure wave is transmitted in the brain. An example of a study of blast-induced neurotrauma can be found in the article http://www.liebertonline.com/doi/abs/10.1089/neu.2008.0602.
There are a number of advantages of using our small size catheter, given its rapid response time and that it can be accurately positioned using either ultrasound or x-ray. Monitoring can take place in the brain itself, in the ventricles which it surrounds or in the subdural space.

 

 

Trauma related ICP